Dinner

Spinach Artichoke Chicken Casserole (Creamy & Cheesy!) Recipe

ByMaya Arden March 23, 2026March 23, 2026

Introduction

This Spinach Artichoke Chicken Casserole is a creamy, cheesy comfort dish that’s perfect for weeknight dinners or casual gatherings. Packed with tender chicken, nutritious spinach, and flavorful artichokes, it’s both satisfying and easy to prepare.

A white baking dish holds a baked spinach and cheese casserole with a golden brown, bubbly melted cheese layer on top, featuring spots of darker brown toasted cheese. The second layer, visible as a scoop is lifted by a spoon held by a woman's hand, shows cooked spinach mixed into a creamy, light-colored sauce with soft textures underneath the crust. The baking dish rests partially on a blue and white striped cloth on a surface with a white marbled texture. Photo taken with an iphone --ar 4:5 --v 7

Ingredients

8 ounces cream cheese (at room temperature)
1 cup plain Greek yogurt (or sour cream)

1 cup shredded mozzarella cheese, divided
⅓ cup grated Parmesan cheese, plus more for topping

1 clove garlic, minced
½ teaspoon kosher salt

¼ teaspoon freshly cracked black pepper
3 cups artichoke hearts, roughly chopped (frozen and defrosted, or canned and drained)
1 (5-ounce) bag baby spinach

2 heaping cups cooked chicken

Instructions

Step 1: Preheat the oven to 375°F (190°C).
Step 2: In a stand mixer bowl, combine cream cheese, Greek yogurt, ½ cup mozzarella, Parmesan, minced garlic, salt, and pepper. Beat with the paddle attachment until smooth and well blended. If you don’t have a mixer, mix thoroughly by hand using a wooden spoon—ensure the cream cheese is very soft.

Step 3: Add chopped artichoke hearts, baby spinach, and cooked chicken to the mixture. Stir gently by hand until everything is evenly incorporated.
Step 4: Lightly spray a 9×13-inch ceramic baking dish with avocado oil or cooking spray. Spread the mixture evenly in the dish. Sprinkle the remaining ½ cup mozzarella and 2 tablespoons Parmesan over the top.
Step 5: Cover the dish with foil and bake for 20 minutes. Remove the foil and bake an additional 5 to 10 minutes, until the top is golden and bubbly.

Step 6: Let the casserole cool for 10 to 15 minutes before slicing to ensure even portions and easier serving.

Tips & Variations

Use fresh garlic instead of minced from a jar for a brighter flavor.
Swap Greek yogurt for sour cream to add richness.

For extra creaminess, add a splash of heavy cream or milk to the cheese mixture.
Add a pinch of red pepper flakes for a subtle spicy kick.
Serve with crusty bread or a side salad to balance the richness.

Storage

Store leftovers covered in the refrigerator for up to 3 days. Reheat individual portions in the microwave or warm the entire dish covered with foil in a 350°F (175°C) oven until heated through. Avoid overheating to prevent the casserole from drying out.

How to Serve

A rectangular white baking dish filled with a baked casserole that has a golden brown and bubbly cheese layer on top. The top cheese layer is unevenly browned with spots of darker crust and lighter creamy areas, showing hints of spinach or greens mixed beneath. The casserole surface has a slightly crispy texture around the edges, and the inside looks creamy with visible green leafy bits. The dish rests on a white marbled surface with a blue and white striped cloth partially underneath, along with some fresh spinach leaves scattered nearby. Two metal serving spoons are placed next to the dish. photo taken with an iphone --ar 4:5 --v 7

Serve this delicious recipe with your favorite sides.

FAQs

Can I use frozen spinach instead of fresh?

Yes, frozen spinach works well. Be sure to thaw and squeeze out excess moisture before adding it to the mixture to prevent the casserole from becoming watery.

Is it necessary to use cooked chicken, or can I use raw?

Cooked chicken is recommended for this recipe to ensure even cooking and to avoid drying out the casserole. You can use leftover rotisserie chicken, grilled chicken, or bake chicken breasts ahead of time.